Novel thermosensitive hydrogel-based fluorescence probe offers fast detection of nitrite

Nitrite (NO₂⁻) is commonly used as a food additive, but when ingested, it can harm the body’s oxygen transport system. The World Health Organization limits NO₂⁻ to 1.0 mg/L in drinking water and 30 mg/kg in meat products. However, current nitrite detection methods are often complicated.

Recently, a team of researchers led by Prof. Jiang Changlong from Institute of Solid State Physics, the Hefei Institutes of Physical Sciences of the Chinese Academy of Sciences, developed a novel thermosensitive hydrogel-based fluorescence probe for real-time visualization and detection of nitrite.

They published the progress in Journal of Hazardous Materials.

“With this probe and a smartphone, the nitrite data is available at a glance,” said Dr. Li Lingfei, a member of the team.

In this research, the functionalized thermosensitive hydrogel doped with fluorescent probes was designed to make it easier to get information of NO₂⁻. Gold nanoclusters (Au NCs) and carbon-based dots were added into the hydrogel’s multi-layered structure, which was made from P407, lignin, and cellulose. This created a material with special fluorescence properties and strong stability. The interconnected P407, lignin, and cellulose gave the hydrogel an excellent porous structure.

This novel Au NCs/LCG-P407 fluorescent hydrogel has been designed with the objective of optimizing portable and efficient device strategies. It provides a basis for further development of sensing platforms for the detection of environmental and hazardous substances in food safety.

The hydrogel sensor can also be paired with a smartphone app to visually measure NO₂⁻ in water, making detection easier and more practical. This research marks an advancement in hydrogel applications and highlights its potential to enhance food safety monitoring systems, according to the team.